Programme
Monday September 5 | |
10:00 – 10:30 | Opening |
10:30 – 11:10 | Petra Ménová, UCT Prague How are new drugs born? |
11:10 – 11:50 | Andrej Michalík, De Clerq & Partners Impact through patents |
11:50 – 12:30 | Daniela Angst, Novartis Discovery of Remibrutinib (LOU064), a covalent and selective BTK inhibitor |
12:30 – 14:00 | Lunch |
14:00 – 14:40 | Ivan Hirsch, Charles University Pathogenesis of SARS-CoV-2 infection |
14:40 – 15:20 | Klára Grantz Šašková, IOCB Prague Lipid nanoparticles for nucleic acid delivery |
15:20 – 15:50 | Coffee Break |
15:50 – 16:30 | Ronen Gabizon, Weizmann Institute of Science Emerging approaches to drug design - covalent Inhibition, molecular glues and targeted degradation |
16:30 – 17:10 | Ori Avinoam, Weizmann Institute of Science A robust, adaptable, high-content screening platform to identify potent broad spectrum viral fusion inhibitors |
19:00 | Welcome Party at Diplomat hotel |
Tuesday September 6 | |
09:00 – 09:40 | Mirko Buchholz, PerioTrap Glutaminyl cyclases as new target proteins: Development of inhibitors and lessons learned |
09:40 – 10:20 | Ariel Bensimon, Solgate Targeting the solute carriers - Developing the drug discovery technology platform |
10:20 – 10:50 | Coffee Break |
10:50 – 11:30 | Christoph Rademacher, University of Vienna From molecular drug targeting to vaccine development |
11:30 – 12:10 | Andrea Brancale, UCT Prague Computer-aided drug design tools to support medicinal chemistry and drug discovery |
12:10 – 14:00 | Lunch |
14:00 – 15:30 | Spin-offs: roundtable discussion Panelists: – Mirko Buchholz – Ariel Bensimon – Christoph Rademacher – Andrea Brancale – Jaromír Zahrádka Host: – Aleš Vlk |
15:30 – 16:00 | Coffee Break |
16:00 – 16:40 | Frank Wagner, Charité Clinical trial design: A paradigm shift in early clinical trials |
16:40 – 17:20 | František Štěpánek, UCT Prague Advanced formulation approaches for bioavailability enhancement of poorly soluble drugs |
Dinner for invited speakers | |
Wednesday September 7 | |
09:00 – 09:40 | Stanislav Rádl, Zentiva Recent progress in the field of prodrugs |
09:40 – 10:20 | Silvia Carvalho, Weizmann Institute of Science Biophysical assays in drug discovery |
10:20 – 10:50 | Coffee Break |
10:50 – 11:30 | Jakub Abramson, Weizmann Institute of Science Exploiting autoimmunity for cancer therapy |
11:30 – 12:10 | Stephan Bachmann, Hoffmann-La Roche Ltd. Catalysis as key technology for the synthesis & scale-up of APIs and their intermediates |
12:10 – 12:50 | Dominik Rejman, IOCB Prague New approaches to combat antibiotic-resistant bacteria |
12:50 – 14:00 | Lunch |
14:00 – 18:00 | Prague City Tour (walking) |
18:00 | Social evening – Karolinum, Charles University, Prague |
Thursday September 8 | |
09:00 – 09:40 | Stella Vukelic, AbbVie Development of CNS penetrating drugs |
09:40 – 10:20 | Javier Terriente, ZeClinics ZeByte: A target discovery platform integrating zebrafish data and artificial intelligence |
10:20 – 10:50 | Coffee Break |
10:50 – 11:30 | Yifat Merbl, Weizmann Institute of Science EpiProteomics in drug discovery |
11:30 – 12:10 | Micha Fridman, Tel Aviv University Chemical biology approaches for deciphering the biological activities of antifungal drugs and improving their performance |
12:10 – 14:00 | Lunch |
14:00 – 14:40 | Pavel Martásek, Biocev Life pigment prospecting: Systems chemical biology approaches to facilitate therapeutic innovation in porphyrias |
14:40 – 15:00 | Haim Barr, Weizmann Institute of Science EU-openscreen ERIC |
15:00 – 18:00 | Poster session |
UCT Tour and Visit of the University Brewery | |
Friday September 9 | |
09:00 – 09:40 | Eva Kudová, IOCB Prague Neurosteroids in health and disease |
09:40 – 10:20 | Donna Matzov,Weizmann Institute of Science Structural biology of GPCRs in the era of cryo-EM |
10:20 – 10:50 | Coffee Break |
10:50 – 11:30 | Ewen Bodio, Université Bourgogne Franche-Comté Design of optical theranostic from in vitro to in vivo |
11:30 – 12:10 | Miroslav Havránek, Apigenex Mitochondrial uncoupler as drug for obesity treatment |
12:10 – 12:50 | Remi Terranova, Novartis Therapeutic modulation of the epigenome - opportunities and challenges |
12:50 – 13:00 | Closing, best poster award winner |